Process Analytical Technology (PAT) refers to a system that provides real-time measurement and analysis of critical parameters during biopharmaceutical process development and manufacture. PAT system tools offer enhanced process understanding and feedback control, enabling advanced control strategies to maintain steady-state reactions in biological processes, thereby ensuring the quality of the final product.

BioAces has independently developed a series of Akwa® PAT products, including Akwa®Cyte and Akwa®Raman, which can improve process efficiency and productivity by detecting problems early in the biotechnology process, and ensure product quality and consistency by closely monitoring critical quality attributes, thereby reducing waste, lowering costs, enhancing efficiency, and facilitating efficient process and technology transfer.

• Continuous real-time in-situ online detection, non-invasive non-destructive testing, without interfering with cellular metabolism
• Akwa®Cyte:

  Label-free, non-staining presentation technology

  Self-developed in-situ online cell sensor

  Patent^{ZL 2020 1 1583924.0}Phase Enhancement System

  AI Image Analysis: Adaptive to various cell lines, Adaptive to bioprocesses, Automatic cell segmentation, Cell aggregation/clustering, Cell apoptosis

• Akwa®Raman:

  High signal collection efficiency (enhanced Raman signals obtained while ensuring high resolution);

  Patented design for efficient sampling signal flux acquisition;

  Realize high signal-to-noise ratio (SNR) within short sampling times;

  Modeling analysis and predictive evaluation by PCA, PLS, and CNN.