Process Analytical Technology (PAT) refers to a system that provides real-time measurement and analysis of key parameters in the biopharmaceutical process. The PAT system tool can provide better process understanding and feedback control, implement advanced control strategies, maintain steady-state reactions in biological processes, and ensure the quality of the final product. Akwa ® R1 is an in-situ Raman analyzer with a built-in standardized universal model and real-time monitoring. Real time online monitoring of key process parameters (CPP) and product quality attributes (CQA) in biological processes to achieve real-time feedback control, thereby supporting customers to improve target protein yield while ensuring product quality, helping biopharmaceutical companies reduce costs and increase efficiency, and complete process development and production more efficiently and stably.

• Standardized Universal Model – Eliminates the need for modeling, ensuring precise compatibility with diverse product types, process scales, and production phases.

• Accurate and Reliable Detection – Results are highly consistent with offline analytical data, guaranteeing accuracy and reproducibility throughout the entire monitoring process.

• Real-Time Continuous Monitoring – Seamless integration with bioreactor control systems via OPC standard interfaces, enabling dynamic feeding strategy optimization based on live data.

• In Situ Monitoring – No sampling required, eliminating contamination risks, and compatible with reactors of various specifications.

• Highly Integrated Plug-and-Play Design – User-friendly software with an intuitive interface for simplified operation.

• Extended Continuous Monitoring (Up to 45 Days) – Supports long-term process development and full-scale production monitoring needs.